… antinociceptive effect of systemically applied medetomidine can be explained by supraspinal
alpha-2-adrenergic mechanisms… systemically administered alpha-2-adrenergic agonists …

… Involvement of supraspinal and spinal segmental alpha-2-adrenergic mechanisms in the
medetomidine-induced antinociception. Neuroscience 44:705714; 1991. …

… the spinal antinociceptive effects with supraspinal ones, the medetomidine-induced effects
… Distributions of mRNAs for alpha-2 adrenergic receptor subtypes in rat brain: An in situ hy…

… the supraspinal level there is an additive antinociceptive interaction … spinal level cocaine
potentiates the medetomidine-induced antinociception independent of supraspinal mechanisms…

… a role in antinociception, as shown by antinociception at the … the hypothesis that
medetomidine-induced sedation is due to … supraspinally applied atipamezole dose, then a,-adrenergic …

… be explained by spinal a,-adrenergic mechanisms. The medetomidine-induced increase of
… purpose was to study the role of a supraspinal structure in antinociception. In spinalized rats …

… for the analgesic properties of alpha-2 adrenergic agonists. In… Involvement of supraspinal
and spinal segmental α2-adrenergic mechanisms in the medetomidine-induced antinociception…

… is mediated at a spinal and, possibly, a supraspinal level, whereas … spinal nerve ligation
may have caused a local disruption of the blood-brain barrier at a segmental level in the spinal …

… Involvement of supraspinal and spinal segmental alpha-2-adrenergic mechanisms in the
medetomidine-induced antinociception. Neuroscience 1991;44:705–714 Wang YC, Su CR, Lin …

… Diencephalic mechanisms of pain sensation … Behavioral and receptor binding analysis of
the alpha-2-adrenergic … the gene coding for the human platelet alpha-2-adrenergic receptor …